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KMID : 0361120160300020069
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Korean Journal of Transplantation
2016 Volume.30 No. 2 p.69 ~ p.76
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Current Status of Solid Organ Xenotransplantation
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Yun Ik-Jin
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Abstract
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Solid organ xenotransplantation using transgenic pig organs is proposed as an alternative method for allo-transplantation. To accomplish this, immunologic and non-immunologic barriers for xenotransplantation should be overcome, and experiments on pigs to non-human primates (NHP) are now ongoing for clinical application. Before the clinical experiment, public consensus about ethical decisions must be considered. The results of NHP experiments on solid organ xenotransplantation are improving, and it is expected that xeno-solid organs can be used as new organs for human patients in the future.
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KEYWORD
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Xenotransplantation, Solid organ transplantation, Transgenic pig
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